You often hear Mac folk talking about Quicksilver and how they love it. It is more than a launcher.
Now there is something interesting in the Windows world (better than adding shortcut keys to your applications).
Enso Launcher is now out in the wild.
I first saw Enso Launcher at the last Ajax Experience, as Aza Raskin was showing it off (and his love for Python).
They also released Enso Words showing off spellcheck everywhere.
So, if you hate the mouse and you are a Windows bloke,
open http://www.humanized.com/products/enso/launcher/ and